https://github.com/smartmonkey-git/phrank-rs

https://github.com/smartmonkey-git/phrank-rs

Last synced: about 2 months ago
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• Host: GitHub
• URL: https://github.com/smartmonkey-git/phrank-rs
• Owner: SmartMonkey-git
• License: mit
• Created: 2026-04-22T13:36:02.000Z (2 months ago)
• Default Branch: main
• Last Pushed: 2026-04-30T08:37:58.000Z (about 2 months ago)
• Last Synced: 2026-04-30T10:23:32.749Z (about 2 months ago)
• Language: Rust
• Size: 158 KB
• Stars: 0
• Watchers: 0
• Forks: 0
• Open Issues: 0
• Metadata Files:
  • Readme: README.md
  • License: LICENSE

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README

          
# Phrank Similarity Engine [![License: MIT][license-badge]][license] [![Static Badge](https://img.shields.io/badge/RobinsonGroup-8A2BE2?style=flat&color=Green)](https://robinsongroup.github.io/)

[license]: https://opensource.org/licenses/MIT

[license-badge]: https://img.shields.io/badge/License-MIT-blue.svg

Phrank is a high-performance, phenotype-driven similarity engine designed to calculate the similarity between patient

cohorts. By leveraging information theory, Phrank quantifies the significance of shared phenotypic features (such as

Human Phenotype Ontology terms) based on their Information Content (IC). This allows for the rarity of a shared

phenotype to dictate the weight of the similarity across the cohort.

The algorithm is available in Rust and Python. Check these distribution platforms for examples

- [Pypi](https://pypi.org/project/phrank-py/)

- [Crate.io](https://crates.io/crates/phrank/0.2.1)

# Credit

Original Publication by Karthik A. Jagadeesh et al. [here](https://www.nature.com/articles/s41436-018-0072-y)