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https://github.com/sorgerlab/earm

Extrinsic Apoptosis Reaction Model
https://github.com/sorgerlab/earm

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Extrinsic Apoptosis Reaction Model

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README

        

EARM
====

Extrinsic Apoptosis Reaction Model

http://sorgerlab.github.com/earm

EARM is a family of models of the extrinsic apoptosis pathway written using the
Python modeling framework PySB. Model variants focus on exploring alternative
hypotheses for the mechanism of Mitochondrial Outer Membrane Permeabilization
(MOMP), controlled by the Bcl-2 family of proteins.

Documentation
-------------

The documentation is available online at http://earm.readthedocs.org/ . The
documentation source files are available locally in the doc/ subdirectory.

Download
--------

EARM is hosted on GitHub at http://github.com/sorgerlab/earm .

The code is available via the Download link there, or you can clone the
repository with Git:

git clone git://github.com/sorgerlab/earm

To use the models you'll need to install PySB and its associated
dependencies. More information on using the models is available in the EARM
documentation.

Authors
-------

Carlos F. Lopez ([email protected])
Jeremy L. Muhlich ([email protected])
John A. Bachman ([email protected])