https://github.com/tskit-dev/msprime
Simulate genealogical trees and genomic sequence data using population genetic models
https://github.com/tskit-dev/msprime
coalescent genetics genomics msprime python simulation trees tskit
Last synced: 3 months ago
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Simulate genealogical trees and genomic sequence data using population genetic models
- Host: GitHub
- URL: https://github.com/tskit-dev/msprime
- Owner: tskit-dev
- License: gpl-3.0
- Created: 2014-09-15T10:25:14.000Z (over 11 years ago)
- Default Branch: main
- Last Pushed: 2025-09-24T16:33:28.000Z (4 months ago)
- Last Synced: 2025-10-17T06:05:18.276Z (3 months ago)
- Topics: coalescent, genetics, genomics, msprime, python, simulation, trees, tskit
- Language: Python
- Homepage:
- Size: 15.3 MB
- Stars: 200
- Watchers: 19
- Forks: 88
- Open Issues: 83
-
Metadata Files:
- Readme: README.md
- Changelog: CHANGELOG.md
- License: LICENSE
- Citation: CITATION.md
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README
# msprime 
[](https://circleci.com/gh/tskit-dev/msprime) [](https://codecov.io/gh/tskit-dev/msprime) [](https://pepy.tech/project/msprime) [](https://anaconda.org/conda-forge/msprime) [](https://archive.softwareheritage.org/browse/origin/?origin_url=https://github.com/tskit-dev/msprime) [](https://github.com/tskit-dev/msprime/actions/workflows/docs.yml) [](https://github.com/tskit-dev/msprime/actions/workflows/wheels.yml) [](https://github.com/tskit-dev/msprime/actions/workflows/tests.yml)
``msprime`` is a population genetics simulator
based on [tskit](https://tskit.dev). Msprime can simulate random
ancestral histories for a sample of individuals
(consistent with a given demographic model) under a
range of different models and evolutionary processes. Msprime can
also simulate mutations on a given ancestral
history (which can be produced by msprime or other programs
supporting [tskit](https://tskit.dev)) under
a variety of genome sequence evolution models.
Please see the [documentation](https://tskit.dev/msprime/docs/latest/) for
more details, including
[installation instructions](https://tskit.dev/msprime/docs/latest/installation.html).