https://uwpr.github.io/Comet/

An tandem mass spectrometry (MS/MS) sequence database search tool.
https://uwpr.github.io/Comet/

Last synced: about 1 year ago
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An tandem mass spectrometry (MS/MS) sequence database search tool.

• Host: GitHub
• URL: https://uwpr.github.io/Comet/
• Owner: UWPR
• License: apache-2.0
• Created: 2021-09-17T17:15:42.000Z (over 4 years ago)
• Default Branch: master
• Last Pushed: 2025-04-23T19:35:02.000Z (about 1 year ago)
• Last Synced: 2025-04-23T20:33:59.572Z (about 1 year ago)
• Language: C
• Homepage: https://uwpr.github.io/Comet/
• Size: 41.3 MB
• Stars: 48
• Watchers: 6
• Forks: 16
• Open Issues: 3
• Metadata Files:
  • Readme: README.md
  • License: LICENSE

Awesome Lists containing this project

• awesome-proteomics - Comet - C++ - Free and open-source search engine, lately it's had several - [paper](https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/pmic.201200439) (3. Raw data search software/algorithms / Table of Contents)

README

          


# Comet MS/MS

Comet is an open source tandem mass spectrometry (MS/MS) sequence database search tool written primarily in C/C++. The original Comet repository lived on [SourceForge](https://sourceforge.net/projects/comet-ms/) since 2012. It was migrated to GitHub on September 2021.

The project website [can be found here](https://uwpr.github.io/Comet/). This includes release notes and search parameters documentation.

To compile on linux and macOS:

- Type 'make'.  This will generate a binary "comet.exe".

To compile with Microsoft Visual Studio:

- Use build tools v142 with Microsoft Visual Studio 2019.

- First install [MSFileReader from Thermo Fischer Scientific](https://uwpr.github.io/Comet/notes/20220228_rawfile.html).

- Load "Comet.sln" in Visual Studio.

- Set the build to "Release" and "x64".

- Right-mouse-click on the "Comet" project and choose "Build". This should generate a binary "Comet.exe" in x64/Release.