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Projects in Awesome Lists tagged with transcriptomics

A curated list of projects in awesome lists tagged with transcriptomics .

https://github.com/scverse/scanpy

Single-cell analysis in Python. Scales to >100M cells.

anndata bioinformatics data-science machine-learning python scanpy scverse transcriptomics visualize-data

Last synced: 11 May 2025

https://github.com/chanzuckerberg/cellxgene

An interactive explorer for single-cell transcriptomics data

dataviz scientific scrna-seq transcriptomics visualization

Last synced: 14 May 2025

https://github.com/owkin/PyDESeq2

A Python implementation of the DESeq2 pipeline for bulk RNA-seq DEA.

bioinformatics differential-expression python rna-seq transcriptomics

Last synced: 09 May 2025

https://github.com/isee/isee

R/shiny interface for interactive visualization of data in SummarizedExperiment objects

clustering dimension-reduction feature-extraction gene-expression gui hacktoberfest human-cell-atlas shiny single-cell transcriptomics visualization

Last synced: 20 Oct 2025

https://github.com/iSEE/iSEE

R/shiny interface for interactive visualization of data in SummarizedExperiment objects

clustering dimension-reduction feature-extraction gene-expression gui hacktoberfest human-cell-atlas shiny single-cell transcriptomics visualization

Last synced: 30 Jul 2025

https://github.com/GoekeLab/bambu

Reference-guided transcript discovery and quantification for long read RNA-Seq data

bambu bioconductor long-reads nanopore nanopore-sequencing r rna-seq rna-seq-analysis transcript-quantification transcript-reconstruction transcriptomics

Last synced: 06 May 2025

https://github.com/goekelab/bambu

Reference-guided transcript discovery and quantification for long read RNA-Seq data

bambu bioconductor long-reads nanopore nanopore-sequencing r rna-seq rna-seq-analysis transcript-quantification transcript-reconstruction transcriptomics

Last synced: 15 May 2025

https://github.com/hms-dbmi/scde

R package for analyzing single-cell RNA-seq data

analysis bioinformatics heterogenity ngs r single-cell transcriptomics

Last synced: 09 Apr 2025

https://github.com/COMBINE-lab/alevin-fry

🐟 🔬🦀 alevin-fry is an efficient and flexible tool for processing single-cell sequencing data, currently focused on single-cell transcriptomics and feature barcoding.

10x quantification rna-seq rust single-cell single-cell-rna-seq transcriptomics

Last synced: 28 Apr 2025

https://github.com/goekelab/xpore

Identification of differential RNA modifications from nanopore direct RNA sequencing

genomics machine-learning modification nanopore nanopore-sequencing python rna rna-modifications rna-seq transcriptomics

Last synced: 16 May 2025

https://github.com/GoekeLab/xpore

Identification of differential RNA modifications from nanopore direct RNA sequencing

genomics machine-learning modification nanopore nanopore-sequencing python rna rna-modifications rna-seq transcriptomics

Last synced: 06 May 2025

https://github.com/alleninstitute/scrattch.hicat

Hierarchical, iterative clustering for analysis of transcriptomics data in R

clustering jaccard r transcriptomics wgcna

Last synced: 12 Apr 2025

https://github.com/goekelab/sg-nex-data

Nanopore RNA-Seq data from the Singapore Nanopore-Expression Project

direct-rna-sequencing long-reads nanopore rna-seq transcriptomics

Last synced: 05 Apr 2025

https://github.com/ZJUFanLab/scDeepSort

Cell-type Annotation for Single-cell Transcriptomics using Deep Learning with a Weighted Graph Neural Network

annotation cell-type-classification deep-learning gnn graph-neural-network reference-free scrna-seq single-cell transcriptomics

Last synced: 21 Jul 2025

https://github.com/JEFworks-Lab/HoneyBADGER

HMM-integrated Bayesian approach for detecting CNV and LOH events from single-cell RNA-seq data

bayesian bioinformatics cnv-detection heterogeneity hmm single-cell-analysis single-cell-rna-seq subpopulation transcriptomics

Last synced: 09 Apr 2025

https://github.com/dib-lab/dammit

just annotate it, dammit!

annotation bioinformatics transcriptomics

Last synced: 19 Jan 2026

https://github.com/novartis/cellxgene-gateway

Cellxgene Gateway allows you to use the Cellxgene Server provided by the Chan Zuckerberg Institute (https://github.com/chanzuckerberg/cellxgene) with multiple datasets.

dataviz h5ad rna-seq scientific scrna-seq transcriptomics visualization

Last synced: 21 Jul 2025

https://github.com/saezlab/cosmosr

COSMOS (Causal Oriented Search of Multi-Omic Space) is a method that integrates phosphoproteomics, transcriptomics, and metabolomics data sets.

data-integration metabolomic-data network-modelling phosphoproteomics proteomics transcriptomics

Last synced: 09 Apr 2025

https://github.com/nathanskene/ewce

Expression Weighted Celltype Enrichment. See the package website for up-to-date instructions on usage.

deconvolution single-cell single-cell-rna-seq transcriptomics

Last synced: 13 Apr 2025

https://github.com/Novartis/cellxgene-gateway

Cellxgene Gateway allows you to use the Cellxgene Server provided by the Chan Zuckerberg Institute (https://github.com/chanzuckerberg/cellxgene) with multiple datasets.

dataviz h5ad rna-seq scientific scrna-seq transcriptomics visualization

Last synced: 28 Sep 2025

https://github.com/theislab/drvi

Unsupervised Deep Disentangled Representation of Single-Cell Omics

anndata bioinformatics disentanglement integration python single-cell transcriptomics

Last synced: 11 Oct 2025

https://github.com/arc85/celltalker

Inference of cell-cell communication from single-cell RNAseq data

ligands receptors single-cell transcriptomics

Last synced: 30 Apr 2025

https://github.com/czbiohub-sf/tabula-sapiens

Single Cell Transcriptomics of 25 Human Organs to Create a Tabula Sapiens

cell-atlas cell-ontologies human-anatomy sapiens single-cell-rna-seq transcriptomics

Last synced: 16 Jan 2026

https://github.com/alleninstitute/scrattch

Single cell RNA-seq analysis for transcriptomic type characterization

r scrattch transcriptomics umbrella

Last synced: 11 Apr 2025

https://github.com/dohlee/chromoformer

The official code implementation for Chromoformer in PyTorch. (Lee et al., Nature Communications. 2022)

artificial-intelligence bioinformatics deep-learning epigenomics gene-expression genomics histone-modifications transcriptomics transformer

Last synced: 29 Apr 2025

https://github.com/paccmann/paccmann_rl

Code pipeline for the PaccMann^RL in iScience: https://www.cell.com/iscience/fulltext/S2589-0042(21)00237-6

de-novo-drug-design deep-learning drug-discovery drug-sensitivity generative-models transcriptomics

Last synced: 28 Mar 2025

https://github.com/orangeSi/GSSplayground

Lightweight single-html-file-based Genome Segments playground for Visualize genome features cluster(gene arrow map or other features), add synteny among genome fragments or add crosslink among features, add short(PE/MP)/long reads(pacbio or nanopore) mapping or snpindel in vcf(not support complex sv yet), support all CIGAR of sam alignment, directly modify almost all features in Chrome by click the feature

bam bioinformatics comparative-genomics crosslink depth genecluster genome-viewer genomes igv-like indel long-reads read-mapping snp structure-variation sv svg synteny transcriptomics vcf visualization

Last synced: 18 Nov 2025

https://github.com/Novartis/pisces

PISCES is a pipeline for rapid transcript quantitation, genetic fingerprinting, and quality control assessment of RNAseq libraries using Salmon.

bioinformatics bioinformatics-pipeline rnaseq rnaseq-pipeline salmon transcriptomics

Last synced: 28 Sep 2025

https://github.com/novartis/pisces

PISCES is a pipeline for rapid transcript quantitation, genetic fingerprinting, and quality control assessment of RNAseq libraries using Salmon.

bioinformatics bioinformatics-pipeline rnaseq rnaseq-pipeline salmon transcriptomics

Last synced: 21 Jul 2025

https://github.com/bayer-group/cellenium

Cellenium is a FAIR and scalable interactive visual analytics app for scRNA-Seq data (single-cell RNA sequencing).

bioinformatics dataviz scrna-seq transcriptomics

Last synced: 12 Apr 2025

https://github.com/Bayer-Group/cellenium

Cellenium is a FAIR and scalable interactive visual analytics app for scRNA-Seq data (single-cell RNA sequencing).

bioinformatics dataviz scrna-seq transcriptomics

Last synced: 28 Sep 2025

https://github.com/alleninstitute/scrattch.vis

scRNA-seq data visualization from scrattch

data-visualization r scrattch transcriptomics

Last synced: 11 Apr 2025

https://github.com/lieberinstitute/spatialdlpfc

spatialDLPFC project involving Visium (n = 30), Visium SPG (n = 4) and snRNA-seq (n = 19) samples

bioconductor dlpfc rstats spatial-transcriptomics spatialdlpfc transcriptomics visium visium-spg

Last synced: 31 Jan 2026

https://github.com/cran-task-views/omics

CRAN Task View: Genomics, Proteomics, Metabolomics, Transcriptomics, and Other Omics

cran genomics metabolomics omics proteomics r rstats task-views transcriptomics

Last synced: 13 Apr 2025

https://github.com/nanoporetech/isonclust2

A tool for de novo clustering of long transcriptomic reads

cdna rna rna-seq transcriptomics

Last synced: 13 Apr 2025

https://github.com/soedinglab/transannot

TransAnnot - a fast transcriptome annotation pipeline

annotation assembly bioinformatics bioinformatics-pipeline transcriptomics

Last synced: 27 Apr 2025

https://github.com/lieberinstitute/vistoseg

Image processing pipeline for spatial projects

matlab spatial transcriptomics visium

Last synced: 16 Aug 2025

https://github.com/almeidasilvaf/hybridexpress

An R package for comparative transcriptomic analyses of hybrids and their progenitors

gene-expression hybrid polyploidy rna-seq transcriptomics

Last synced: 20 Oct 2025

https://github.com/transbiozi/biomm

BioMM: Biological-informed Multi-stage Machine learning framework for phenotype prediction using omics data

biomm dna-methylation elasticnetregression epigenomics gene-expression genomics go-pathway gwas high-dimensional kegg-pathway machine-learning omics phenotype-prediction random-forest svm transcriptomics

Last synced: 29 Oct 2025

https://github.com/krassowski/gsea-api

Pandas API for multiple Gene Set Enrichment Analysis implementations in Python (GSEApy, cudaGSEA, GSEA)

bioinformatics cuda enrichment gene-set-enrichment gene-sets gsea pandas pathway-analysis python3 transcriptomics

Last synced: 13 Apr 2025

https://github.com/delosh653/echo

An application to find and visualize circadian rhythms in time course data using extended harmonic oscillators.

bioinformatics bioinformatics-tool circadian circadian-rhythm circadian-rhythmicity echo extended-harmonic-oscillators finding-rhythms omics oscillators proteomics transcriptomics

Last synced: 11 Apr 2025

https://github.com/ocbe-uio/discbio

A user-friendly R pipeline for biomarker discovery in single-cell transcriptomics

biomarker-discovery jupyter-notebook r-package scrna-seq single-cell-analysis transcriptomics

Last synced: 11 Jul 2025

https://github.com/alleninstitute/scrattch.io

Functions for handling RNA-seq files and formats as input and output for scrattch functions.

10xgenomics hdf5 loom r tome transcriptomics

Last synced: 03 Aug 2025

https://github.com/wukevin/rnagps

Interpretable model of sub-cellular RNA localization.

interpretable-machine-learning transcriptomics

Last synced: 10 Apr 2025

https://github.com/theislab/mapqc

MapQC - a metric for the evaluation of single-cell query-to-reference mappings

atlas integration mapping query-to-reference-mapping single-cell transcriptomics

Last synced: 11 Oct 2025

https://github.com/alleninstitute/tasic2016data

Single cell transcriptomic data from Tasic, et al. (2016)

scrattch scrna-seq-data transcriptomics

Last synced: 11 Apr 2025

https://github.com/paccmann/paccmann_omics

Generative models for transcriptomics profiles and proteins

deep-learning generative-model proteomics transcriptomics vae variational-autoencoder

Last synced: 10 Apr 2025

https://github.com/UcarLab/iasva

Iteratively Adjusted Surrogate Variable Analysis

heterogeneity heuristic-algorithm r single-cell single-cell-rna-seq transcriptomics

Last synced: 08 Apr 2025

https://github.com/benfulcher/allensdk

Workflow for retrieving spatial gene-expression data from the Allen Institute's Mouse Brain Atlas

bioinformatics geneexpression transcriptomics

Last synced: 13 May 2025

https://github.com/noncodo/bigredbutton

Pipeline for the unsupervised clustering of homologous RNA structure motifs from sequencing data.

bioinformatics genome-annotation lncrna rna-structure transcriptomics

Last synced: 21 Jan 2026

https://github.com/lieberinstitute/visium_spg_ad

Visium SPG AD project (n = 10) using Visium Spatial Proteogenomics (Visium-SPG) on dissections from the inferior temporal cortex (ITC) from Alzheimer's disease cases and controls.

alzheimers-disease bioconductor rstats spatial-transcriptomics transcriptomics visium visium-spg visium-spg-ad

Last synced: 06 Jan 2026

https://github.com/anergictcell/atg

A Rust library and CLI tool to handle genomic transcripts

bioinformatics bioinformatics-tool cli-app converter genomics gtf transcriptomics

Last synced: 24 Apr 2025

https://github.com/microbiomedata/metat

Metatranscriptomics workflow

metatranscriptomics transcriptomics workflow

Last synced: 27 Oct 2025

https://github.com/epigen/macrophage-regulation

Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation

atac-seq bioinformatics crispr crop-seq epigenomics immunology perturb-seq perturbations rna-seq scrna-seq systems-biology systems-immunology time-series transcriptomics

Last synced: 03 Aug 2025

https://github.com/sales-lab/spatialde

R wrapper for SpatialDE

python r spatial-data transcriptomics wrapper

Last synced: 05 May 2025

https://github.com/tcp-lab/biotea

bioTEA - A user friendly tool to perform transcript expression analysis

bioinformatics-tool command-line-tool differential-gene-expression docker linux microarray python transcriptomics

Last synced: 30 Aug 2025

https://github.com/antonkulaga/genotations

A small library to work with ensembl and other annotations in python

annotations bioinformatics ensembl genes genomics gtf polars transcriptomics

Last synced: 07 Sep 2025

https://github.com/microsoft/scfm-datamix

Assessing the influence of training data composition on single-cell foundation model performance

foundation-models genomics rna-seq single-cell transcriptomics

Last synced: 22 Mar 2025

https://github.com/raw-lab/metaome_stats

Statistical package for metaome denovo assembly results.

fasta genome metagenome metagenome-assembly metaome-stats metatranscriptomics transcriptomics

Last synced: 16 Jan 2026

https://github.com/dhimmel/stargeo

Generating expression signatures for disease using STARGEO

diseases gene-expression hetionet meta-analysis microarray-data rephetio stargeo transcriptomics

Last synced: 23 Mar 2025

https://github.com/dhimmel/bgee

Extracting anatomy-specific gene expression in humans from Bgee

anatomy bgee gene gene-expression hetionet rephetio transcriptomics tsv

Last synced: 09 Oct 2025

https://github.com/nuno-agostinho/phd-thesis

Developing Web Apps for Analyses of Transcriptomes

transcriptomics webapp

Last synced: 08 Nov 2025

https://github.com/stracquadaniolab/cubseq-nf

CUBseq analyses codon usage bias from RNA-seq data, producing robust CUB estimates that account for variants transcriptome-wide and in highly expressed genes.

codon-bias codon-optimization codon-usage nextflow rnaseq transcriptomics

Last synced: 17 Oct 2025

https://github.com/saezlab/hepatic-microenviroment

Gut microbiota fuels HCC development by shaping the hepatic inflammatory microenvironment

cancer hcc liver microbiome r transcriptomics

Last synced: 22 Jul 2025

https://github.com/thomasgust/elastic-st

A python data science library to build and analyze biological networks from spatial transcriptomics data. Allows inclusion of spatial information into the networks, going a step beyond graphs derived from scRNA-seq techniques.

bioinformatics biological-networks cython data-science linear-models machine-learning python spatial-transcriptomics spatial-transcriptomics-networks transcriptomics

Last synced: 26 Sep 2025

https://github.com/arunbodd/arunbodd.github.io

The website showcases Arun Boddapati's professional portfolio, emphasizing his expertise as a bioinformatics scientist and machine learning expert.

bioinformatics bioinformatics-analysis bioinformatics-pipeline infectious-diseases machinelearning metagenomics nextflow public-health surveillance transcriptomics

Last synced: 23 Jul 2025

https://github.com/tcp-lab/mtp-db

The Membrane Transport Protein Database

phd-project transcriptomics transportome

Last synced: 22 Feb 2025

https://github.com/k8hertweck/cancer_genomics

Example workflow for cancer genomics analysis using TCGA data

cancer genomics tcgabiolinks transcriptomics

Last synced: 03 Mar 2025

https://github.com/lieberinstitute/deconvo_lute-paper

Contains analysis for the lute software paper

bioconductor deconvolution neuroscience r transcriptomics

Last synced: 16 Jul 2025

https://github.com/saezlab/liver-disease-atlas

Transcriptomic cross-species analysis of chronic liver disease reveals consistent regulation between humans and mice

bioinformatics liver-disease meta-analysis transcriptomics workflowr

Last synced: 15 Mar 2025

https://github.com/stefanpeidli/scperturb_snakemake_example

Example repository for analyzing many datasets at once from scperturb.org using snakemake

perturbation-methods single-cell transcriptomics

Last synced: 04 Apr 2025

https://github.com/broadinstitute/temporal-rna-seq-deconvolution

Package for temporal deconvolution of bulk RNA-seq samples using SVI

deconvolution pyro rna-seq single-cell-rna-seq svi transcriptomics

Last synced: 20 Feb 2025

https://github.com/gauravcodepro/genomic-alignment-extraction

A scalable large scale genomic fraction aligner and extractor for the large scale alignment of the genomes and the transcriptomes and process them over the cores for the extraction of the aligned regions. The aligned regions can also be mapped to the length plotter and can be machine trained for specific applications

alignment-algorithms alignmentextract alignments genome genome-annotation genome-assembly genomealignment transcriptome-analysis transcriptomealignment transcriptomics

Last synced: 22 Feb 2025

https://github.com/ellfran-7/cluefish

A specialised workflow designed to enhance the biological interpretation of transcriptomic data series 🎣

interpretation r transcriptomics workflow

Last synced: 26 Oct 2025

https://github.com/sing-group/dreimt-backend

A Java backend for the DREIMT application

drug-repositioning immune-system transcriptomics

Last synced: 03 Jul 2025