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awesome-proteomics

An awesome list of proteomics tools and resources
https://github.com/lyons89/awesome-proteomics

Last synced: 7 days ago
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  • 7. Protein Pathway Enrichment

    • Table of Contents

      • fgsea - R - fast gene set enrichment analysis - [paper](https://www.biorxiv.org/content/10.1101/060012v2.full)
      • pathfindR - R - active subnetwork oriented pathway enrichment analyses that uses protein-protein ineteraction networks to enchance the standard pathway analysis method - [paper](https://www.frontiersin.org/articles/10.3389/fgene.2019.00858/full)
      • phosphoRWHN - R - pathway enrichment for phosphoproteomics data - [paper](https://pubs.acs.org/doi/10.1021/acs.jproteome.1c00150)
      • leapR - R - package for multiple pathway analysis - [paper](https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00963)
      • fgsea - R - fast gene set enrichment analysis - [paper](https://www.biorxiv.org/content/10.1101/060012v2.full)
      • leapR - R - package for multiple pathway analysis - [paper](https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00963)
  • 8. Kinase Motif/Activity Analysis

    • Table of Contents

      • KSEAapp - R - Kinase substrate enrichment analysis. I would recommend using with a freshly downloaded kinase-substarte database from phosphositeplus - [paper](https://pubmed.ncbi.nlm.nih.gov/28655153/)
      • rnotifx - R - motif enrichment analyssis of PTMs on proteins, probably mostly used for phosphorylation - [paper](https://pubmed.ncbi.nlm.nih.gov/26572964/)
      • KSEAapp - R - Kinase substrate enrichment analysis. I would recommend using with a freshly downloaded kinase-substarte database from phosphositeplus - [paper](https://pubmed.ncbi.nlm.nih.gov/28655153/)
  • 9. Top down data analysis

    • Table of Contents

      • ClipsMS - python - analysis of terminal and internal fragments in top-down mass spectrometry data - [paper](https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00952)
  • Miscellaneous

    • Table of Contents

      • cytoscape - visualizing protein-protein interaction netweorks
      • ProteoWizard - Great software for converting one MS file type to another. I mostly use it ot convert thermo .raw files to mzML - [paper](https://www.nature.com/articles/nbt.2377)
      • IPSC - Interactive Peptide Spectrum Annotator, web based utility for shotgun mass spectrum annotation - [paper](https://www.mcponline.org/article/S1535-9476(20)32771-7/fulltext)
      • PeCorA - R - peptide correlation analysis - [paper](https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00602)
      • ProteaseGuru - C# - tool for In Silico Database Digestion, optimize bottom up experiments - [paper](https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00954)
      • DeepLC - python - predicts retention times for peptides that have unseen modifications - [paper](https://www.nature.com/articles/s41592-021-01301-5)