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https://github.com/aces/mni-models_adni_nl


https://github.com/aces/mni-models_adni_nl

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1) MNI ADNI non-linear asymmetric Average Brain Stereotaxic Registration Model

This is a version of the ADNI Average Brain - an average of ???
T1-weighted MRI scans, linearly and non-linearly (?? iterations)
transformed to form an asymmetric model in Talairach space - that
is specially adapted for use with the MNI Linear Registration
Package (mni_autoreg).

Included in this package are the following files:

mni_adni_t1w_tal_nlin_asym.mnc:
a version of the average MRI that covers the whole brain
(unlike the original Talairach atlas), sampled with 1mm cubic
voxels
mni_adni_t1w_tal_nlin_asym_mask.mnc, mni_adni_t1w_tal_nlin_asym_mask.obj:
a mask of the average brain in mni_adni_t1w_tal_nlin_asym.mnc.mnc,
semi-automatically created by Vladimir Fonov. Note that
this mask has had holes filled in, so it is a connected volume
but includes non-brain tissue (eg. the CSF in the ventricles)
mni_adni_t1w_tal_nlin_asym_headmask.mnc:
another mask (full head mask), required for nonlinear mode
mni_adni_t1w_tal_nlin_asym_vent.mnc, mni_adni_t1w_tal_nlin_asym_vent.obj:
a mask of the ventricles
mni_adni_t1w_tal_nlin_asym_ntags_1000_bg.tag:
tag points for the background for mni_adni_t1w_tal_nlin_asym.mnc
mni_adni_t1w_tal_nlin_asym_ntags_1000_nobg.tag
tag points for the CSF, GM, and WM for mni_adni_t1w_tal_nlin_asym.mnc
Cerebellum_Ventricles_SubCortical_Mask-ADNI.mnc:
a template for the cerebellum, brain-stem, ventricles and sub-cortical
gray to be used in the CIVET pipeline
to_icbm152_2009a.xfm, to_icbm152_2009a_grid_0.mnc:
a non-linear transform to map the ADNI model to the MNI-ICBM152-2009a
model.

2) MNI ADNI non-linear symmetric Average Brain Stereotaxic Registration Model, hi-resolution

This is a version of the ADNI Average Brain - an average of ???
T1-weighted MRI scans, linearly and non-linearly (?? iterations)
transformed to form an asymmetric model in Talairach space - that
is specially adapted for use with the MNI Linear Registration
Package (mni_autoreg). The voxel resolution of this model is 0.5mm
isotropic.

Included in this package are the following files:

mni_adni_hi_t1w_tal_nlin_sym.mnc:
a version of the average MRI that covers the whole brain
(unlike the original Talairach atlas), sampled with 1mm cubic
voxels
mni_adni_hi_t1w_tal_nlin_sym_mask.mnc, mni_adni_t1w_tal_nlin_asym_mask.obj:
a mask of the average brain in mni_adni_t1w_tal_nlin_asym.mnc.mnc,
semi-automatically created by Vladimir Fonov. Note that
this mask has had holes filled in, so it is a connected volume
but includes non-brain tissue (eg. the CSF in the ventricles)
mni_adni_hi_t1w_tal_nlin_sym_headmask.mnc:
another mask (full head mask), required for nonlinear mode
mni_adni_hi_t1w_tal_nlin_sym_vent.mnc, mni_adni_hi_t1w_tal_nlin_sym_vent.obj:
a mask of the ventricles
mni_adni_hi_t1w_tal_nlin_sym_ntags_1000_bg.tag:
tag points for the background for mni_adni_t1w_tal_nlin_asym.mnc
mni_adni_hi_t1w_tal_nlin_sym_ntags_1000_nobg.tag:
tag points for the CSF, GM, and WM for mni_adni_t1w_tal_nlin_asym.mnc
gipt_adnihisym.mnc:
a mask for sub-cortical gray that is used to define the sub-cortical
tissue class in PVE
Cerebellum_Ventricles_SubCortical_Mask-ADNIhi.mnc:
a template for the cerebellum, brain-stem, ventricles, sub-cortical
gray, hippocampus, amygdala, to be used in the CIVET pipeline
hi_to_icbm152_2009b.xfm, hi_to_icbm152_2009b_grid_0.mnc:
a non-linear transform to map the hi-res ADNI sym model to the MNI-ICBM152-2009b
model (warning: it's not very accurate).

3) References:

Fonov, V., Coupe, P., Eskildsen, S., Collins, L., and The Alzheimers’s Disease Neuroimaging Initiative (2011).
Atrophy specific MRI brain template for Alzheimer’s disease and Mild Cognitive Impairment.
Alzheimer’s Association International Conference, July 2011, France. 7 (4), pp. S58, 2011.
https://hal.archives-ouvertes.fr/hal-00645521
https://drive.google.com/file/d/0B2WB9sZf0qcZTzUxZDU1QWRJRVE/view