https://github.com/alro10/nonlinear-fitting-kinetics-dnaandrnap
Nonlinear regression using to estimate kinetics constants of DNA promoter opening and escape during transcription initiation complex assembled between Lambda PR promoter and E. coli RNA polymerase.
https://github.com/alro10/nonlinear-fitting-kinetics-dnaandrnap
exponential fitting nonlinear-regression rna rna-polymerase
Last synced: 3 months ago
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Nonlinear regression using to estimate kinetics constants of DNA promoter opening and escape during transcription initiation complex assembled between Lambda PR promoter and E. coli RNA polymerase.
- Host: GitHub
- URL: https://github.com/alro10/nonlinear-fitting-kinetics-dnaandrnap
- Owner: Alro10
- License: mit
- Created: 2019-04-14T19:20:29.000Z (about 7 years ago)
- Default Branch: master
- Last Pushed: 2019-04-16T01:55:49.000Z (about 7 years ago)
- Last Synced: 2025-12-28T04:29:31.916Z (6 months ago)
- Topics: exponential, fitting, nonlinear-regression, rna, rna-polymerase
- Size: 52.7 KB
- Stars: 1
- Watchers: 0
- Forks: 0
- Open Issues: 0
-
Metadata Files:
- Readme: README.md
- License: LICENSE
Awesome Lists containing this project
README
# Nonlinear fitting kinetics DNA and RNAP
Nonlinear regression using to estimate kinetics constants of DNA promoter opening and escape during transcription initiation complex assembled between Lambda PR promoter and E. coli RNA polymerase. Based on [Kinetics of promoter escape by bacterial RNA polymerase: effects of
promoter contacts and transcription bubble collapse](https://www.researchgate.net/publication/263709791_Kinetics_of_promoter_escape_by_bacterial_RNA_polymerase_Effects_of_promoter_contacts_and_transcription_bubble_collapse).
under developing!
## Requirements
```
numpy =1.16.2
scipy = 1.2.1
matplotlib = 1.5.1
```
## Approach
**What is a simple method to fit and estimate constants of that exponential function?**
## User guide