https://github.com/bio2bel/hmdd

A Bio2BEL package for converting the Human microRNA Disease Database (HMDD) to BEL
https://github.com/bio2bel/hmdd

biological-expression-language microrna phenotypes systems-biology

Last synced: 6 months ago
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A Bio2BEL package for converting the Human microRNA Disease Database (HMDD) to BEL

• Host: GitHub
• URL: https://github.com/bio2bel/hmdd
• Owner: bio2bel
• License: apache-2.0
• Created: 2017-06-25T09:39:44.000Z (about 9 years ago)
• Default Branch: master
• Last Pushed: 2018-11-21T21:20:35.000Z (over 7 years ago)
• Last Synced: 2025-09-14T08:48:26.815Z (10 months ago)
• Topics: biological-expression-language, microrna, phenotypes, systems-biology
• Language: Jupyter Notebook
• Homepage: http://bio2bel-hmdd.rtfd.io
• Size: 35.2 KB
• Stars: 0
• Watchers: 2
• Forks: 0
• Open Issues: 1
• Metadata Files:
  • Readme: README.rst
  • License: LICENSE

Awesome Lists containing this project

README

          
Bio2BEL HMDD |docs|

===================

Converts the Human microRNA Disease Database to BEL

Citation

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Li Y, Qiu C, Tu J, et al. HMDD v2.0: a database for experimentally supported human microRNA and disease associations. Nucleic Acids Research. 2014;42(Database issue):D1070-D1074. doi:10.1093/nar/gkt1023.

Abstract

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HMDD (the Human microRNA Disease Database) is a database that curated experiment-supported evidence for human microRNA (miRNA) and disease associations. miRNAs are one class of important regulatory RNAs, which mainly repress gene express at the post-transcriptional level. Increasing reports have shown that miRNAs play important roles in various critical biological processes. For their importance, the dysfunctions of miRNAs are associated with a broad spectrum of diseases. The first version of HMDD was built on December 2007. Each entry in HMDD v1.0 has four items for annotation; they are miRNA name, disease name, the reference PubMed ID, and the evidence supporting the miRNA-association from the original paper. During the past five years, we updated HMDD for more than 30 times. HMDD v2.0 presents more detailed and comprehensive annotations to the human miRNA-disease association data, including miRNA-disease association data from the evidence of genetics, epigenetics, circulating miRNAs, and miRNA-target interactions. In addition, a “submission” function was implemented in the version 2.

Links

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- Database: http://www.cuilab.cn/hmdd

- Data: http://www.cuilab.cn/files/images/hmdd2/alldata.txt

.. |docs| image:: http://readthedocs.org/projects/bio2bel-hmdd/badge/?version=latest

    :target: http://bio2bel.readthedocs.io/projects/hmdd/en/latest/?badge=latest

    :alt: Documentation Status