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https://github.com/bionf/phyloprofile-data

Data files for PhyloProfile tool
https://github.com/bionf/phyloprofile-data

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Data files for PhyloProfile tool

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# PhyloProfile Test and Experimental Data

This repository contains **test input files** and **experimental datasets** for the [**PhyloProfile**](https://bioconductor.org/packages/PhyloProfile) tool.

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## Demo Datasets

The archives **`ampk-tor.zip`** and **`arthropoda.zip`** include data for two demo datasets used by PhyloProfile.
These datasets are also available through [**Bioconductor ExperimentHub**](https://bioconductor.org/packages/release/bioc/html/ExperimentHub.html) via the **PhyloProfileData** package (source code can be found [here](https://github.com/BIONF/PhyloProfileData)).

They are used to demonstrate how to run PhyloProfile and analyze its results.
Briefly, it contains phylogenetic profiles, FASTA sequences, and domain annotations for two experimental datasets:

- **AMPK–TOR pathway dataset:**
147 human proteins involved in the AMPK–TOR pathway across 83 species.
- **Arthropoda dataset:**
1,011 BUSCO arthropoda ortholog groups across 88 species spanning the three domains of life.

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## Other Experimental Data

The **`otherExpTestData`** folder contains two additional experimental datasets.
These can be downloaded and manually provided to PhyloProfile for testing or analysis.

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## Demo Input Files

The **`demoInput`** folder includes several example input files in various formats.
To learn how to correctly format input data for PhyloProfile, please refer to our [**Wiki page**](https://github.com/BIONF/PhyloProfile/wiki/Input-Data).

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## References

Ngoc-Vinh Tran, Bastian Greshake Tzovaras, Ingo Ebersberger, PhyloProfile: dynamic visualization and exploration of multi-layered phylogenetic profiles, Bioinformatics, Volume 34, Issue 17, 01 September 2018, Pages 3041–3043, https://doi.org/10.1093/bioinformatics/bty225