https://github.com/cbg-ethz/geneaccord
GeneAccord: An R package to detect patterns of mutual exclusivity and co-occurrence on the clone level in a cohort of cancer patients
https://github.com/cbg-ethz/geneaccord
cancer clonal cooccurrence exclusivity mutual
Last synced: 6 months ago
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GeneAccord: An R package to detect patterns of mutual exclusivity and co-occurrence on the clone level in a cohort of cancer patients
- Host: GitHub
- URL: https://github.com/cbg-ethz/geneaccord
- Owner: cbg-ethz
- License: gpl-3.0
- Created: 2018-03-07T09:21:36.000Z (over 7 years ago)
- Default Branch: master
- Last Pushed: 2021-09-10T09:56:46.000Z (about 4 years ago)
- Last Synced: 2024-08-09T00:21:43.186Z (about 1 year ago)
- Topics: cancer, clonal, cooccurrence, exclusivity, mutual
- Language: R
- Homepage:
- Size: 2.96 MB
- Stars: 2
- Watchers: 4
- Forks: 0
- Open Issues: 0
-
Metadata Files:
- Readme: README.md
- License: LICENSE
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README
# GeneAccord #
This R package has functions to detect clonal exclusivity or co-occurrence patterns of altered genes or pathways in a cohort of cancer patients. Such clonally exclusive gene pairs may uncover synergies between co-existing clones.
The file geneAccord_AML.R reads in the data from the AML cohort and runs the three different GeneAccord tests on the data.
### Contacts ###
Jack Kuipers ( jack.kuipers __ bsse.ethz.ch )