https://github.com/fcampelo/epitopes2
Secret sauce for our epitope prediction and optimisation pipelines
https://github.com/fcampelo/epitopes2
Last synced: 4 days ago
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Secret sauce for our epitope prediction and optimisation pipelines
- Host: GitHub
- URL: https://github.com/fcampelo/epitopes2
- Owner: fcampelo
- Created: 2023-04-10T10:31:32.000Z (about 3 years ago)
- Default Branch: main
- Last Pushed: 2026-06-20T15:33:59.000Z (14 days ago)
- Last Synced: 2026-06-20T16:21:09.689Z (14 days ago)
- Language: R
- Size: 371 MB
- Stars: 0
- Watchers: 2
- Forks: 0
- Open Issues: 0
-
Metadata Files:
- Readme: README.md
- Changelog: NEWS.md
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README
# epitopes package
[](https://github.com/fcampelo/epitopes/actions)
Processing, Feature Extraction and modelling of epitope data from the Immune Epitope Database ([IEDB](http://iedb.org))
## Authors:
- Felipe Campelo - [f.campelo@aston.ac.uk](mailto:f.campelo@aston.ac.uk), [fcampelo@gmail.com](mailto:fcampelo@gmail.com)
## Collaborators:
- Francisco Lobo - [franciscolobo@ufmg.br](mailto:franciscolobo@ufmg.br)
## Previous contributors:
- Jodie Ashford - [ashfojsm@aston.ac.uk](mailto:ashfojsm@aston.ac.uk)
- Joao Reis-Cunha - [jaumlrc@gmail.com](jaumlrc@gmail.com)
## Current version:
- Consolidation of linear B-cell epitopes from the full IEDB database and
retrieval of protein data from NBCI and Uniprot.
- Organism- and taxon-based filtering of epitope data.
- Data splitting for machine learning based on protein dissimilarity.
- Extraction of observations for feature calculation using a sliding window representation.
- Calculation of sequence-based features.
- Read prediction output from other predictors (ABCPred, Bepipred 2.0, iBCE-EL, LBtope, SVMTrip)
- Fitting classification models to data with hold-out set-based assessment.
## Upcoming:
- Plotting functions
## Usage
Check Vignette [Usage example](https://fcampelo.github.io/epitopes/articles/Usage-example.html) for a quick tutorial.
***
Please report any bugs or suggestions directly in the repository [Issues](https://github.com/fcampelo/epitopes/issues) page.