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https://github.com/pysam-developers/pysam

Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.
https://github.com/pysam-developers/pysam

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Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.

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README

        

=====
Pysam
=====

|build-status| |docs|

Pysam is a python module for reading and manipulating files in the
SAM/BAM format. The SAM/BAM format is a way to store efficiently large
numbers of alignments (`Li 2009`_), such as those routinely created by
next-generation sequencing methods.

Pysam is a lightweight wrapper of the samtools_ C-API. Pysam also
includes an interface for tabix_.

If you are using the conda packaging manager (e.g. miniconda or anaconda),
you can install pysam from the `bioconda channel `_::

conda config --add channels defaults
conda config --add channels conda-forge
conda config --add channels bioconda
conda install pysam

Installation through bioconda is the recommended way to install pysam
as it resolves non-python dependencies and uses pre-configured
compilation options. Especially for OS X this will potentially save a
lot of trouble.

The current version of pysam wraps 3rd-party code from htslib-1.18, samtools-1.18, and bcftools-1.18.

Pysam is available through `pypi
`_. To install, type::

pip install pysam

Pysam documentation is available
`here `_

Questions and comments are very welcome and should be sent to the
`pysam user group `_

.. _samtools: http://samtools.sourceforge.net/
.. _tabix: http://samtools.sourceforge.net/tabix.shtml
.. _Li 2009: http://www.ncbi.nlm.nih.gov/pubmed/19505943

.. |build-status| image:: https://github.com/pysam-developers/pysam/actions/workflows/ci.yaml/badge.svg
:alt: build status
:scale: 100%
:target: https://github.com/pysam-developers/pysam/actions/workflows/ci.yaml

.. |docs| image:: https://readthedocs.org/projects/pysam/badge/?version=latest
:alt: Documentation Status
:scale: 100%
:target: https://pysam.readthedocs.org/en/latest/?badge=latest