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https://github.com/vanheeringen-lab/seq2science

Automated and customizable preprocessing of Next-Generation Sequencing data, including full (sc)ATAC-seq, ChIP-seq, and (sc)RNA-seq workflows. Works equally easy with public as local data.
https://github.com/vanheeringen-lab/seq2science

atac-seq bioinformatics bioinformatics-pipeline chip-seq fastq ngs pipeline reproducible-research rna-seq snakemake sra workflows

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Automated and customizable preprocessing of Next-Generation Sequencing data, including full (sc)ATAC-seq, ChIP-seq, and (sc)RNA-seq workflows. Works equally easy with public as local data.

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README

        

# seq2science
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Seq2science is the attempt of the *van heeringen lab* to generate a collection of generic pipelines/workflows which can be used by complete beginners to bioinformatics and experienced bioinformaticians alike. Please take a look at our [docs](https://vanheeringen-lab.github.io/seq2science/) for help with installation, how to run it, and best practices.

![alt text](https://vanheeringen-lab.github.io/seq2science/_static/seq2science.png "seq2science")

Our supported workflows:
* [Downloading of fastq](https://vanheeringen-lab.github.io/seq2science/content/workflows/download_fastq.html)
* [Alignment](https://vanheeringen-lab.github.io/seq2science/content/workflows/alignment.html)
* [ATAC-seq](https://vanheeringen-lab.github.io/seq2science/content/workflows/atac_seq.html)
* [RNA-seq](https://vanheeringen-lab.github.io/seq2science/content/workflows/rna_seq.html)
* [ChIP-seq](https://vanheeringen-lab.github.io/seq2science/content/workflows/chip_seq.html)
* [scATAC-seq](https://vanheeringen-lab.github.io/seq2science/content/workflows/scatac_seq.html)
* [scRNA-seq](https://vanheeringen-lab.github.io/seq2science/content/workflows/scrna_seq.html)

## New users
Information for new users, such as how to install and configure can be found in our [getting started](https://vanheeringen-lab.github.io/seq2science/content/gettingstarted.html) page, and our [Frequently Asked Questions (FAQ)](https://vanheeringen-lab.github.io/seq2science/content/faq.html) section.

## Feedback
Anything not working as expected? Please reach out to us via our [issues](https://github.com/vanheeringen-lab/seq2science/issues) page and we'll try to help you as soon as possible!

## Cite us
van der Sande M, Frölich S, Schäfers T, Smits JGA, Snabel RR, Rinzema S, van Heeringen SJ. 2023. Seq2science: an end-to-end workflow for functional genomics analysis. PeerJ 11:e16380 https://doi.org/10.7717/peerj.16380