https://github.com/cardiacmodelling/rapidcharacterisationprotocols

Collection of experimental protocols in common patch clamp formats for rapid characterisation of ion channels

electrophysiology herg ion-channel-kinetics ion-channels patch-clamp voltage-clamp

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/markov-builder

Tool for building and manipulating Markov models of ion-channel kinetics

herg herg-channel-kinetics markov-model python

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/fourwaysoffitting

Code to compare four different ways to fit an ion current model

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/ionbench

A benchmarking tool for comparing different parameter optimization algorithms for ion channel models

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/hergrapidcharacterisation

Rapid characterisation of hERG channel kinetics

electrophysiology herg herg-channel-kinetics high-throughput ion-channels modeling patch-clamp temperature-dependence voltage-clamp

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/voltageclampmodel

Code to add a mathematical model of voltage-clamp artefacts to your ion channel simulations

artefacts electrophysiology herg high-throughput ion-channel-kinetics modeling patch-clamp variability voltage-clamp

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/fickleheart-method-tutorials

Code for the tutorials in the Fickle Heart model calibration with discrepancy 2020 paper.

autoregressive-moving-average bayesian-inference calibration electrophysiology gaussian-processes model-discrepancy uncertainty-quantification

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/wires

Figures and code for examples in WIREs review on calibrating electrophysiology models

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/herg-binding-mechanisms

Source code and data for reproducing "The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk".

drug-binding drug-induced-arrhythmias herg in-silico uncertainty

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/ina-midpoints

Data and figures for "Variability in reported midpoints of (in)activation for cardiac INa"

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/continuationforoptimisation

Using limit cycle continuation methods to speed up evaluation of ion channel cell models

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/apd90_ex_vivo_vs_in_silico

Code to reproduce the figures and results from "Comparison of in silico predictions of action potential duration in response to inhibition of IKr and ICaL with new human ex-vivo recordings"

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/nonlinear-time-dependent-leak

Data and code for reproducing the results in the nonlinear time-dependent leak paper.

calcium-fluoride high-throughput patch-clamp voltage-clamp

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/tailored-ipsc-models

Code to reproduce the simulations and figures in "Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology"

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/ical-model-review

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/gamma_0

Code associated with a publication on the action potential model parameter representing missing charge

action-potential cardiac-electrophysiology cardiac-modelling

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/voltageclampapi

A python web api for the artefacts app

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/multiprotocol_data_fitting

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/glycan-counter

Scripts for counting glycans in images

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/covid19-data-current

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/.github

.github special repo for organisation level readme file

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/action-potential-experimental-design

Experimental design for calibrating action potential models.

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/cellml-repo-updates

Adding or updating models in the CellML model repository

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/cside-2018

Code for the Glasgow CSide 2018 cardiac fitting competition https://www.gla.ac.uk/schools/mathematicsstatistics/events/conferences/cside2018/models/model1/

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/stochastic-gating

Code to replicate the analyses from the article "Parameter inference for stochastic reaction models of ion channel gating from whole-cell voltage-clamp data"

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/r56q-modelling

A repository to reproduce modelling results for the R56Q-hERG project

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/atriallowk

Effect on low external K on atrial myocytes via IK1 and INaK

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/fitting-with-derivatives-cinc

Code for the CINC paper "Derivative-based Inference for Cell and Channel Electrophysiology Models"

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/protocol-design-herg

Voltage clamp protocol design for hERG.

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/risk-stratification-anti-malarials

Code and figures for cardiac risk assessment of hydroxycholoroquine and other anti-infective compounds using the qNet classifier

Last synced: 05 Mar 2026

https://github.com/cardiacmodelling/eadpredict

Code to reproduce the results in the paper "Early afterdepolarisation tendency as a simulated pro-arrhythmic risk indicator"

Last synced: 05 Mar 2026