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Projects in Awesome Lists by PaccMann

A curated list of projects in awesome lists by PaccMann .

https://github.com/paccmann/paccmann_predictor

PyTorch implementation of bimodal neural networks for drug-cell (pharmarcogenomics) and drug-protein (proteochemometrics) interaction prediction

deep-learning drug-interaction drug-sensitivity pharmacogenomics proteochemometrics pytorch

Last synced: 11 Feb 2025

https://github.com/paccmann/paccmann_proteomics

PaccMann models for protein language modeling

protein-language-model pytorch transformer

Last synced: 10 Apr 2025

https://github.com/paccmann/paccmann_kinase_binding_residues

Comparison of active site and full kinase sequences for drug-target affinity prediction and molecular generation. Full paper: https://pubs.acs.org/doi/10.1021/acs.jcim.1c00889

active-sites kinases knn machine-learning protein-ligand-interactions proteochemometrics

Last synced: 10 Apr 2025

https://github.com/paccmann/paccmann_rl

Code pipeline for the PaccMann^RL in iScience: https://www.cell.com/iscience/fulltext/S2589-0042(21)00237-6

de-novo-drug-design deep-learning drug-discovery drug-sensitivity generative-models transcriptomics

Last synced: 28 Mar 2025

https://github.com/paccmann/titan

Code for "T Cell Receptor Specificity Prediction with Bimodal Attention Networks" (https://doi.org/10.1093/bioinformatics/btab294, ISMB 2021)

compound-protein-interaction deep-learning immunology protein-ligand tcr-epitope

Last synced: 10 Apr 2025

https://github.com/paccmann/paccmann_datasets

pytoda - PaccMann PyTorch Dataset Classes. Read the docs: https://paccmann.github.io/paccmann_datasets/

bioinformatics chemoinformatics deep-learning python pytorch rdkit smiles

Last synced: 09 Apr 2025

https://github.com/paccmann/paccmann_sarscov2

Code for paper on automation of discovery and synthesis of targeted molecules: https://iopscience.iop.org/article/10.1088/2632-2153/abe808

accelerated-discovery computer-aided-synthesis-planning de-novo-drug-design deep-learning drug-discovery proteochemometrics sars-cov-2

Last synced: 28 Mar 2025

https://github.com/paccmann/fdsa

A fully differentiable set autoencoder

deep-learning multimodal-data set-autoencoder

Last synced: 10 Apr 2025

https://github.com/paccmann/paccmann_chemistry

Generative models of chemical data for PaccMann^RL

deep-learning drug-discovery generative-model molecule-generation vae

Last synced: 10 Apr 2025

https://github.com/paccmann/paccmann_generator

Generative models for transcriptomic-driven or protein-driven molecular design (PaccMann^RL).

deep-reinforcement-learning drug-discovery generative-model molecule-generation vae

Last synced: 10 Apr 2025

https://github.com/paccmann/paccmann_gp

PyTorch/skopt based implementation of Bayesian optimization with Gaussian processes - build to optimize latent spaces of VAEs to generate molecules with desired properties

bayesian-optimization chemoinformatics gaussian-processes generative-model machine-learning

Last synced: 10 Apr 2025

https://github.com/paccmann/paccmann_omics

Generative models for transcriptomics profiles and proteins

deep-learning generative-model proteomics transcriptomics vae variational-autoencoder

Last synced: 10 Apr 2025

https://github.com/paccmann/paccmann_polymer

Graph-regularized VAE and the impact of topology on learned representations

deep-learning gnn graph-regularized-vae manifold-learning pytorch vae

Last synced: 28 Mar 2025

https://github.com/paccmann/reinvent_models

PaccMann fork of Reinvent Models

Last synced: 28 Mar 2025

https://github.com/paccmann/paccmann.github.io

PaccMann website

Last synced: 28 Mar 2025

https://github.com/paccmann/docs

Documentation for PaccMann service

Last synced: 28 Mar 2025