Projects in Awesome Lists by Merck
A curated list of projects in awesome lists by Merck .
https://github.com/Merck/BioPhi
BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody sequence design.
antibody humanization humanness oasis sapiens
Last synced: 09 May 2025
https://github.com/merck/biophi
BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody sequence design.
antibody humanization humanness oasis sapiens
Last synced: 07 Apr 2025
https://github.com/merck/deepbgc
BGC Detection and Classification Using Deep Learning
bidirectional-lstm biosynthetic-gene-clusters deep-learning deepbgc natural-products pfam2vec python synthetic-biology
Last synced: 07 Apr 2025
https://github.com/Merck/deepbgc
BGC Detection and Classification Using Deep Learning
bidirectional-lstm biosynthetic-gene-clusters deep-learning deepbgc natural-products pfam2vec python synthetic-biology
Last synced: 09 May 2025
https://github.com/merck/halyard
Halyard is an extremely horizontally scalable Triplestore with support for Named Graphs, designed for integration of extremely large Semantic Data Models, and for storage and SPARQL 1.1 querying of the whole Linked Data universe snapshots.
Last synced: 22 Apr 2025
https://github.com/Merck/Halyard
Halyard is an extremely horizontally scalable Triplestore with support for Named Graphs, designed for integration of extremely large Semantic Data Models, and for storage and SPARQL 1.1 querying of the whole Linked Data universe snapshots.
Last synced: 09 May 2025
https://github.com/merck/r2rtf
Easily Create Production-Ready Rich Text Format (RTF) Table and Figure
Last synced: 16 May 2025
https://github.com/Merck/r2rtf
Easily Create Production-Ready Rich Text Format (RTF) Table and Figure
Last synced: 28 Sep 2025
https://github.com/Merck/matcher
Matcher is a tool for understanding how chemical structure optimization problems have been solved. Matcher enables deep control over searching structure/activity relationships (SAR) derived from large datasets, and takes the form of an accessible web application with simple deployment. Matcher is built around the mmpdb platform.
chemistry docker-compose drug-discovery search-algorithm search-engine web-application
Last synced: 28 Sep 2025
https://github.com/merck/sapiens
Sapiens is a human antibody language model based on BERT.
antibody bert embeddings language-model sapiens
Last synced: 22 Apr 2025
https://github.com/merck/matcher
Matcher is a tool for understanding how chemical structure optimization problems have been solved. Matcher enables deep control over searching structure/activity relationships (SAR) derived from large datasets, and takes the form of an accessible web application with simple deployment. Matcher is built around the mmpdb platform.
chemistry docker-compose drug-discovery search-algorithm search-engine web-application
Last synced: 25 Jul 2025
https://github.com/Merck/Sapiens
Sapiens is a human antibody language model based on BERT.
antibody bert embeddings language-model sapiens
Last synced: 28 Sep 2025
https://github.com/merck/rdf2x
RDF2X converts big RDF datasets to the relational database model, CSV, JSON and ElasticSearch.
conversion json linked-data postgresql rdf spark sparql sql
Last synced: 22 Apr 2025
https://github.com/Merck/rdf2x
RDF2X converts big RDF datasets to the relational database model, CSV, JSON and ElasticSearch.
conversion json linked-data postgresql rdf spark sparql sql
Last synced: 28 Sep 2025
https://github.com/Merck/Line-of-Therapy-Algorithm
This is the Line of Therapy Algorithm, as described in the paper "Temporal phenotyping by mining healthcare data to derive lines of therapy for cancer" pending submission in the Journal of Biomedical Informatics.
Last synced: 28 Sep 2025
https://github.com/merck/line-of-therapy-algorithm
This is the Line of Therapy Algorithm, as described in the paper "Temporal phenotyping by mining healthcare data to derive lines of therapy for cancer" pending submission in the Journal of Biomedical Informatics.
Last synced: 18 Aug 2025
https://github.com/Merck/pkglite
Compact Package Representations
clinical-trials ectd package packaging-tool pharmaverse r
Last synced: 29 Jul 2025
https://github.com/merck/pkglite
Compact Package Representations
clinical-trials ectd package packaging-tool pharmaverse r
Last synced: 27 Aug 2025
https://merck.github.io/pkglite/
Compact Package Representations
clinical-trials ectd package packaging-tool pharmaverse r
Last synced: 24 Apr 2025
https://github.com/merck/simtrial
Clinical trial simulation for time-to-event endpoints
Last synced: 21 Aug 2025
https://github.com/Merck/sonar-r-plugin
Adds support for R language into SonarQube. It uses output from lintr tool which is processed by the plugin and uploaded into SonarQube server.
Last synced: 28 Sep 2025
https://github.com/merck/gsdesign2
Group Sequential Design Under Non-Proportional Hazards
Last synced: 21 Aug 2025
https://github.com/merck/sonar-r-plugin
Adds support for R language into SonarQube. It uses output from lintr tool which is processed by the plugin and uploaded into SonarQube server.
Last synced: 22 Apr 2025
https://github.com/merck/algebraicagents.jl
A lightweight framework to enable hierarchical, heterogeneous dynamical systems co-integration. Batteries included!
differential-equations dynamical-systems julia julia-language stochastic-processes
Last synced: 10 Apr 2025
https://github.com/Merck/AlgebraicAgents.jl
A lightweight framework to enable hierarchical, heterogeneous dynamical systems co-integration. Batteries included!
differential-equations dynamical-systems julia julia-language stochastic-processes
Last synced: 28 Sep 2025
https://github.com/merck/molprop
fuses molecular language and graph representation for property prediction
Last synced: 05 Oct 2025
https://github.com/merck/metalite.ae
An R package for standard adverse events analysis
cdisc clinical-trials metadata r-package
Last synced: 22 Apr 2025
https://github.com/merck/reactivedynamics.jl
A Julia package that implements a category of reaction (transportation) network-type dynamical systems.
decision-making differential-equations julia-language optimization reaction-network scientific-machine-learning strategic-planning
Last synced: 07 May 2025
https://github.com/Merck/ReactiveDynamics.jl
A Julia package that implements a category of reaction (transportation) network-type dynamical systems.
decision-making differential-equations julia-language optimization reaction-network scientific-machine-learning strategic-planning
Last synced: 28 Sep 2025
https://github.com/Merck/metalite
An R package to create metadata structure for ADaM data analysis and reporting
cdisc clinical-trials metadata r-package
Last synced: 29 Jul 2025
https://github.com/merck/pmpo
Probabilistic Multi-Parameter Optimization (pMPO)
Last synced: 22 Apr 2025
https://github.com/merck/metalite
An R package to create metadata structure for ADaM data analysis and reporting
cdisc clinical-trials metadata r-package
Last synced: 22 Aug 2025
https://github.com/merck/biophi-2021-publication
This repository contains scripts, data and jupyter notebooks used to produce the evaluation results in the BioPhi 2021 publication
Last synced: 22 Apr 2025
https://github.com/merck/boxly
Interactive box plot for clinical trial analysis
Last synced: 22 Apr 2025
https://github.com/merck/forestly
Interactive forest plot for adverse events analysis
Last synced: 22 Apr 2025
https://github.com/merck/ablef
Antibody Langauge Ensemble Fusion - fuses antibody structural ensemble and language representation for property prediction
Last synced: 22 Apr 2025
https://github.com/merck/psm3mkv
psm3mkv: A package to evaluate the fit and efficiency of three state oncology cost-effectiveness model structures
Last synced: 22 Apr 2025
https://github.com/merck/generatedexpressions.jl
A Julia package that implements a metalanguage to support expression comprehensions.
julia-language metaprogramming
Last synced: 02 Sep 2025
https://github.com/merck/gmcpshiny
A Shiny app for graphical multiplicity control
clinical-trial-design graphical-approach group-sequential-designs multiple-testing multiplicity r-package rshiny-application
Last synced: 22 Apr 2025
https://github.com/merck/rtdpy
Residence Time Distribution modeling in Python.
process-development python residence-time-distribution
Last synced: 22 Apr 2025
https://github.com/merck/ceedesigns.jl
A decision-making framework for the cost-efficient design of experiments, balancing the value of acquired experimental evidence and incurred costs.
decision-making experimental-design julia-language
Last synced: 15 Sep 2025
https://github.com/merck/gmcplite
Lightweight graph-based multiple comparison procedures
Last synced: 05 Mar 2026
https://github.com/merck/compoundcomplexity
This is an implementation of Compound Complexity for use in the SMART-PMI as described by Sherer et al. It contains derived training data as required by the described Random Forest Model in order to replicate data presented in paper as well as applying to novel data.
Last synced: 14 Mar 2026
https://github.com/merck/simvaxpmx
Elucidating vaccine efficacy using a correlate of protection, demographics, and logistic regression
Last synced: 25 Jun 2025
https://github.com/merck/polo
POLO: web interface to MARCO-scored crystallization images
Last synced: 22 Apr 2025
https://github.com/merck/real-world-time-to-treatment-discontinuation-prediction-algorithm
Real-world Time to Treatment Discontinuation Prediction Algorithm
Last synced: 17 Jul 2025
https://github.com/merck/curation-open-source
This wrapper enables the HPC execution of FDA DB curation and list all the step in a programming language style.
Last synced: 27 Sep 2025
https://github.com/merck/message-hub
The Messaging Orchestration HUB will be responsible for providing a connection between an organization's GS1 EPCIS-based track and trace data source system (for example ATTP) and the blockchain networks that require data relevant to product serialization and track & trace.
Last synced: 27 Sep 2025
https://github.com/merck/parmsurv
a SAS marco on parametric survival analysis
Last synced: 10 Mar 2026
https://github.com/merck/bayesiansprt
The goal of bayesiansprt (under GPL-3 license) is to provide the results for sequential probability ratio test under frequentist and Bayesian setup.
Last synced: 11 Mar 2025
https://github.com/merck/deker
This library is made to perform feature selection based on a method originally proposed in by Sun et al. [1]. This library specifically relates to the methodology described in [2], named DEKER for decomposed kernel regression, which includes methods for identifying optimal hyperparameter values. This library was also designed for use in the context of network inference, also described in [2], by iteratively reapplying the DEKER method for feature selection across all features of a dataset.
Last synced: 27 Sep 2025
https://github.com/merck/spc_package
Rspc is an implementation of nelson rules for control charts in R.
Last synced: 22 Apr 2025
https://github.com/merck/metalite.sl
An R package designed for the analysis & reporting of subject baseline characteristics in clinical trials.
Last synced: 02 Aug 2025
https://github.com/merck/linea
Linea is a DocGraph tool that is designed to be a digital catalogue of publically available healthcare related datasets.
Last synced: 30 Oct 2025
https://github.com/merck/nlp-slr-corpora
The use of systematic literature reviews (SLR) is an important tool for life-science research. SLRs are manually intensive procedures involving selection and retrieval of relevant publications, typically by human review of their abstracts. The shared two disease-specific corpora were developed for this purpose. One is for human papillomavirus (HPV) associated diseases and the other is for pneumococcal-associated pediatric diseases (PAPD).
Last synced: 19 Mar 2026