OBO Foundry
The mission of the OBO Foundry is to develop a family of interoperable ontologies that are both logically well-formed and scientifically accurate. To achieve this, OBO Foundry participants follow and contribute to the development of an evolving set of principles including open use, collaborative development, non-overlapping and strictly-scoped content, and common syntax and relations, based on ontology models that work well, such as the Operations Committee with Editorial, Technical and Outreach working groups.
- GitHub: https://github.com/topics/obofoundry
- Wikipedia: https://en.wikipedia.org/wiki/OBO_Foundry
- Repo: https://github.com/OBOFoundry
- Released: 2003
- Related Topics: web-ontology-language, owl, owl-ontology,
- Aliases: obo,
- Last updated: 2026-05-29 00:19:10 UTC
- JSON Representation
https://github.com/monarch-initiative/ontogpt
LLM-based ontological extraction tools, including SPIRES
ai chat-gpt data-modeling gpt-3 information-extraction language-models large-language-models linkml llm monarchinitiative named-entity-recognition ner nlp oaklib obofoundry relation-extraction
Last synced: 08 Apr 2025
https://github.com/BFO-ontology/BFO
BFO repository including source code and latest documents
Last synced: 03 Apr 2025
https://github.com/incatools/ontology-development-kit
Ontology lifecycle management
continuous-integration monarchinitiative obo obofoundry ontology owl protege robot travis
Last synced: 22 Jul 2025
https://github.com/monarch-initiative/mondo
Mondo Disease Ontology
disease disease-classification monarchinitiative mondo obofoundry ontology owl
Last synced: 16 May 2025
https://github.com/althonos/pronto
A Python frontend to (Open Biomedical) Ontologies.
bioinformatics obo obo-graphs obofoundry ontology owl parser python semantic-web
Last synced: 16 May 2025
https://github.com/biolink/biolink-model
Schema and generated objects for biolink data model and upper ontology
biolink datamodel gene-ontology json-api knowledge-graphs linkml monarchinitiative ncats ncats-translator neo4j obofoundry owl rdf specification standard yaml
Last synced: 06 May 2026
https://github.com/obophenotype/cell-ontology
An ontology of cell types
anatomy anatomy-ontology cell-ontology cell-types genomics metazoa monarchinitiative obofoundry ontology owl semantic-web transcriptomics
Last synced: 16 Apr 2026
https://biolink.github.io/biolink-model/
Schema and generated objects for biolink data model and upper ontology
biolink datamodel gene-ontology json-api knowledge-graphs linkml monarchinitiative ncats ncats-translator neo4j obofoundry owl rdf specification standard yaml
Last synced: 06 May 2025
https://github.com/callahantiff/pheknowlator
PheKnowLator: Heterogeneous Biomedical Knowledge Graphs and Benchmarks Constructed Under Alternative Semantic Models
benchmarks biolink-model biomedical-applications bioregistry hacktoberfest knowledge-graph linked-open-data mechanisms obofoundry ontologies owl semantic-web translational-research
Last synced: 05 Apr 2025
https://github.com/FoodOntology/foodon
The core repository for the FOODON food ontology project. This holds the key classes of the ontology; larger files and the results of text-mining projects will be stored in other repos.
agriculture food obofoundry ontology owl
Last synced: 03 Apr 2025
https://github.com/incatools/ontology-access-kit
Ontology Access Kit: A python library and command line application for working with ontologies
apis geneontology monarchinitiative oaklib obofoundry ontology ontology-api owl python rdf semantic-web
Last synced: 12 Apr 2026
https://github.com/mapping-commons/sssom
Simple Standard for Sharing Ontology Mappings
linkml mapping mapping-commons mapping-standards mapping-tools metadata-elements obofoundry owl sssom tsv
Last synced: 11 Mar 2025
https://github.com/EnvironmentOntology/envo
A community-driven ontology for the representation of environments
data-management data-science earth-science ecoinformatics ecology environment esip obofoundry ontology planetary-science semantics sustainable-development-goals
Last synced: 03 Apr 2025
https://github.com/biolink/ontobio
python library for working with ontologies and ontology associations
bioinformatics gene-ontology graph obo obofoundry ontology ontology-tools python rdf semantic-web sparql
Last synced: 16 May 2025
https://github.com/oborel/obo-relations
RO is an ontology of relations for use with biological ontologies
bfo knowledge-graph obo-relations obofoundry ontologies owl relations
Last synced: 27 Jan 2026
https://github.com/EBISPOT/OLS
Ontology Lookup Service from SPOT at EBI
java neo4j obofoundry owl owl-api
Last synced: 09 May 2025
https://github.com/callahantiff/omop2obo
OMOP2OBO: A Python Library for mapping OMOP standardized clinical terminologies to Open Biomedical Ontologies
clinical-terminologies hacktoberfest obofoundry omop omop-cdm open-biomedical-ontologies translational-research
Last synced: 20 Jun 2025
https://github.com/monarch-initiative/curategpt
LLM-driven curation assist tool
ai biocuration curation gpt llm monarchinitiative obofoundry ontogpt ontologies ontology-tools
Last synced: 05 Apr 2025
https://github.com/obi-ontology/obi
The Ontology for Biomedical Investigations
bioinformatics obo obofoundry ontology owl semantic-web
Last synced: 11 Mar 2025
https://github.com/information-artifact-ontology/IAO
information artifact ontology
Last synced: 03 Apr 2025
https://github.com/biopragmatics/pyobo
📛 A Python package for using ontologies, terminologies, and biomedical nomenclatures
bioinformatics biopragmatics bioregistry obo obofoundry ontologies
Last synced: 04 Apr 2025
https://github.com/monarch-initiative/maxo
Medical action ontology
diagnostics interventions medical medicine monarchinitiative obofoundry ontology owl treatment treatments
Last synced: 19 Jan 2026
https://github.com/jannahastings/emotion-ontology
Ontology for emotions and affective phenomena
affective-sciences emotion-ontology obofoundry
Last synced: 14 Jul 2025
https://github.com/pato-ontology/pato
PATO - the Phenotype And Trait Ontology
obo obofoundry ontology phenotypes qualities quantities semantic-web standards trait-ontology units
Last synced: 03 Apr 2025
https://github.com/monarch-initiative/sepio-ontology
Ontology for representing scientific evidence and provenance information
evidence monarchinitiative obofoundry provenance
Last synced: 21 Jan 2026
https://github.com/monarch-initiative/koza
Data transformation framework for LinkML data models
etl knowledge-graph koza linkml monarchinitiative obofoundry ontology
Last synced: 07 May 2026
https://github.com/incatools/ubergraph
Integrated OBO ontology store
knowledge-graph ncats-translator obofoundry owl rdf
Last synced: 05 Mar 2026
https://github.com/planteome/plant-trait-ontology
Explore the Plant Trait Ontology on the Planteome site.
obo obofoundry owl phenotype plant-trait-ontology plant-traits
Last synced: 16 Jan 2026
https://github.com/evidenceontology/evidenceontology
Evidence & Conclusion Ontology development site: Use ISSUES to request terms. See WIKI for how to request terms. See README for how to cite ECO. Visit our website for more project info.
annotation evidence obo obofoundry ontology owl
Last synced: 11 Mar 2025
https://github.com/incatools/dead_simple_owl_design_patterns
A simple system for specifying OWL class design patterns for OBO-ish ontologies.
obofoundry odp ontology templates
Last synced: 19 Jun 2025
https://github.com/incatools/semantic-sql
SQL and SQLite builds of OWL ontologies
linkml oaklib obofoundry ontologies owl relation-graph sparql sql
Last synced: 05 Apr 2025
https://github.com/vemonet/shapes-of-you
💠 An index for linked open data & standard knowledge descriptions (ontologies, vocabularies, shapes, queries, mappings)
git grlc index mappings obofoundry ontologies owl registry shacl shacl-shapes shapes shex skos sparql
Last synced: 15 Jun 2025
https://github.com/allysonlister/swo
The Software Ontology (SWO) is a resource for describing software tools, their types, tasks, versions, licences, provenance and associated data.
Last synced: 03 Apr 2025
https://github.com/rsc-ontologies/rxno
Name Reaction Ontology
molecular-processes obo obofoundry owl reaction-ontology
Last synced: 11 May 2025
https://github.com/ISA-tools/stato
This is the development repository for the STATistics Ontology (STATO). For more information and demonstration on the ontology content, please visit its website:
obofoundry ontology owl statistics
Last synced: 11 Mar 2025
https://github.com/fastobo/fastobo-py
Faultless AST for Open Biomedical Ontologies in Python.
ast obo obofoundry ontology parser python-bindings python-extension rust
Last synced: 17 Mar 2026
https://github.com/obophenotype/ncbitaxon
Build for NCBITaxon
ncbi-taxonomy obofoundry ontology taxonomy
Last synced: 16 Apr 2026
https://github.com/knowledge-graph-hub/kg-obo
A package to transform all OBO ontologies into KGX TSV format and OBO json, and put the transformed graph in KGhub
biolink knowledge-graph monarchinitiative obo obofoundry ontology-infrastructure
Last synced: 25 Jan 2026
https://github.com/fastobo/fastobo
Faultless AST for Open Biomedical Ontologies.
Last synced: 11 Mar 2025
https://github.com/cmungall/semantic-llama
A knowledge extraction tool that uses a large language model to extract semantic information from text
ai knowledge-extraction language-models linkml oaklib obofoundry
Last synced: 05 May 2025
https://github.com/incatools/dosdp-tools
Utility for working with DOSDP design patterns and OWL ontologies
design-patterns dosdp-pattern monarchinitiative obofoundry odp ontology owl
Last synced: 03 Sep 2025
https://github.com/jannahastings/mental-functioning-ontology
Ontology for all aspects of human mental functioning
mentalfunctioning obofoundry ontologies ontology
Last synced: 08 Jan 2026
https://github.com/incatools/boomer
Bayesian OWL ontology merging
boomer geneontology monarchinitiative mondo obofoundry ontology-merging owl owl-ontology probabilistic-owl reasoning
Last synced: 01 Mar 2025
https://github.com/INCATools/obographviz
Customizable translation of OBO graphs to dot for visualization using graphviz and other tools
graph-visualization graphviz javascript json node obofoundry obographs
Last synced: 11 Mar 2025
https://github.com/incatools/obographviz
Customizable translation of OBO graphs to dot for visualization using graphviz and other tools
graph-visualization graphviz javascript json node obofoundry obographs
Last synced: 11 Apr 2025
https://github.com/biopragmatics/curies
🐸 Idiomatic conversion between URIs and compact URIs (CURIEs) in Python
curies obofoundry semantic-web uris
Last synced: 07 Apr 2025
https://github.com/bio-ontology-research-group/unit-ontology
An ontology of units of measurements
obo obofoundry ontology units-of-measurement
Last synced: 25 Jan 2026
https://github.com/BiodiversityOntologies/bco
Biological Collections Ontology
Last synced: 11 Mar 2025
https://github.com/CIDO-ontology/cido
CIDO: Coronavirus Infectious Disease Ontology
coronavirus covid-19 infectious-diseases mers-cov obofoundry ontology sars-cov sars-cov-2
Last synced: 11 Mar 2025
https://github.com/OBOFoundry/OBO-Dashboard
Summary Dashboard for Open Biological and Biomedical Ontologies
Last synced: 11 Mar 2025
https://github.com/chemkg/chemrof
Schema for chemistry ontology classes
chebi chemistry linkml metaclass obo obofoundry ontology owl schema
Last synced: 28 Feb 2026
https://github.com/mgijax/mammalian-phenotype-ontology
Standard terms for annotating mammalian phenotypic data
json mammals obo obofoundry ontology owl phenotype phenotyping
Last synced: 05 Feb 2026
https://github.com/drseb/hpo-translations
Internationalisation of the HPO content
hpo hpo-translations language obofoundry ontology phenomics phenotype-ontologies phenotypes phenotyping semantic-web translation
Last synced: 21 Jan 2026
https://github.com/data2health/contributor-role-ontology
This ontology provides contribution roles for use in crediting persons or organizations.
Last synced: 11 Mar 2025
https://github.com/OGMS/ogms
Automatically exported from code.google.com/p/ogms
Last synced: 11 Mar 2025
https://github.com/monarch-initiative/GENO-ontology
Repository for representing genotypes and their association with phenotypes
monarchinitiative obofoundry ontology
Last synced: 11 Mar 2025
https://github.com/planteome/plant-stress-ontology
An ontology containing biotic and abiotic plant stresses. Part of the Planteome suite of reference ontologies. Formerly called the Ontology of Plant Stress
abiotic-stresses biotic-stresses obo obofoundry ontology plant-stress
Last synced: 12 Jan 2026
https://github.com/incatools/kgcl-rdflib
Tools for working with KGCL
diff diffs kg knowledge-graph linkml obofoundry ontology ontology-change-language owl rdf semantic-diff
Last synced: 07 Sep 2025
https://github.com/monarch-initiative/geno-ontology
Repository for representing genotypes and their association with phenotypes
monarchinitiative obofoundry ontology
Last synced: 22 Jan 2026
https://github.com/BFO-ontology/BFO2
BFO 2 classes with relations commonly used by OBO Foundry ontologies defined in RO core
Last synced: 11 Mar 2025
https://github.com/semanticchemistry/semanticchemistry
Chemical Information Ontology
chemical-information cheminformatics chemistry obofoundry ontology
Last synced: 11 Mar 2025
https://github.com/pcastellanoescuder/FoodBiomarkerOntology
:rocket: Food-Biomarker Ontology defines the relationships between foods and their associated metabolites (biomarkers) through a formal ontology
biomarkers foods knowledge-graph metabolomics nutrition obofoundry ontologies ontology
Last synced: 11 Mar 2025
https://github.com/pcastellanoescuder/foodbiomarkerontology
:rocket: Food-Biomarker Ontology defines the relationships between foods and their associated metabolites (biomarkers) through a formal ontology
biomarkers foods knowledge-graph metabolomics nutrition obofoundry ontologies ontology
Last synced: 28 Oct 2025
https://github.com/pombase/fypo
Fission Yeast Phenotype Ontology
fission-yeast obofoundry phenotypes pombase
Last synced: 16 Jan 2026
https://github.com/incatools/relation-graph
Materialize OWL existential relations
Last synced: 01 Mar 2025
https://github.com/PopulationAndCommunityOntology/pco
An ontology about groups of interacting organisms such as populations and communities
Last synced: 11 Mar 2025
https://github.com/monarch-initiative/monochrom
Standardized identifiers and OWL classes for chromosomes and chromosomal parts across species
ai4curation chromosomes etl genomics linkml monarchinitiative obofoundry owl
Last synced: 29 Oct 2025
https://github.com/DIDEO/DIDEO
The Potential Drug-drug Interaction and Potential Drug-drug Interaction Evidence Ontology (DIDEO)
Last synced: 11 Mar 2025
https://github.com/planteome/plant-experimental-conditions-ontology
Repository for the Plant Experimental Conditions Ontology
exposures obo obofoundry owl plant-treatments
Last synced: 28 Jan 2026
https://github.com/rsc-ontologies/rsc-cmo
Chemical Methods Ontology
chemical-methods-ontology chromatography obo obofoundry ontology owl
Last synced: 11 May 2025
https://github.com/linkml/prefixmaps
Semantic prefix map registry
bioregistry linkml obofoundry prefixmaps
Last synced: 23 Apr 2025
https://github.com/obophenotype/biological-spatial-ontology
An ontology for respresenting spatial concepts, anatomical axes, gradients, regions, planes, sides, and surfaces
anatomy anatomy-ontology metazoa obofoundry spatial
Last synced: 16 Apr 2026
https://github.com/linkml/sparqlfun
sparql templates for linkml (alpha)
linked-data linkml obofoundry ontobee ontologies rdflib sparql sparql-templates ubergraph
Last synced: 23 Apr 2025
https://github.com/speciesfilegroup/nomen
A nomenclatural ontology for names (not concepts).
nomen nomenclature obofoundry ontology taxa taxon taxonomy web-ontology-language
Last synced: 09 Feb 2026
https://github.com/obophenotype/provisional_cell_ontology
Draft cell type definitions from data - candidates for inclusion in CL
cell-ontology cell-types obofoundry ontology single-cell-analysis single-cell-rna-seq transcriptomics
Last synced: 16 Apr 2026
https://github.com/obophenotype/brain_data_standards_ontologies
A repository for co-ordinating work on ontologies for the Brain Data Standards Project
anatomy-ontology brain brain-data cell-types metadata neuroanatomy neuron obofoundry ontology
Last synced: 16 Apr 2026
https://github.com/ClinicalTrialOntology/CTO
CTO: Core Ontology of Clinical Trials
clinical-trials obofoundry ontology
Last synced: 11 Mar 2025
https://github.com/obophenotype/c-elegans-phenotype-ontology
Ontology for phenotypes pertaining to the nematode Caenorhabditis elegans and related nematodes used by the nematode genome database WormBase
caenorhabditis-elegans elegans elegans-phenotype-ontology nematodes obofoundry ontology phenotype-ontologies phenotype-term phenotypes
Last synced: 16 Apr 2026
https://github.com/monarch-initiative/ontorunner
concept-recognition monarchinitiative nlp obofoundry
Last synced: 03 Aug 2025
https://github.com/cthoyt/curies4j
🐸 Idiomatic conversion between URIs and compact URIs (CURIEs)
curies java obofoundry semantic-web uris
Last synced: 10 Apr 2025
https://github.com/cmungall/sweet-obo-alignment
Alignment between ESIP SWEET and Open Bio Ontologies
environment environment-variables mapping obo obofoundry ontology sssom sweet
Last synced: 08 Jan 2026
https://github.com/evoinfo/miapa
Minimum Information About a Phylogenetic Analysis (MIAPA) vocabularies and tools
information-exchange minimum-information obofoundry phylogenetics standard
Last synced: 11 Mar 2025
https://github.com/obophenotype/zebrafish-phenotype-ontology
A vocabulary for describing Zebrafish Phenotypes
anatomy anatomy-ontology developmental-stages obofoundry ontology zebrafish
Last synced: 16 Apr 2026
https://github.com/ebi-biomodels/sbo
The Systems Biology Ontology (SBO) is a set of controlled, relational vocabularies of terms commonly used in Systems Biology, and in particular in computational modeling.
biosimulators computational-biology mathematical-modeling numerical-simulation obofoundry ontology sbml systems-biology
Last synced: 25 Apr 2026
https://github.com/chemkg/c3p
LLM-generated CHEBI classifiers
artificial-intelligence chebi chemistry large-language-models monarch-initative obofoundry rdkit
Last synced: 30 Aug 2025
https://github.com/monarch-initiative/babelon
A format for language profiles for ontologies
internationalization language-translation linkml monarchinitiative obofoundry owl semantic-web
Last synced: 25 Feb 2026
https://github.com/obophenotype/fungal-anatomy-ontology
A structured controlled vocabulary for the anatomy of fungi
anatomy anatomy-ontology fungi obofoundry ontology
Last synced: 16 Apr 2026
https://github.com/EBI-BioModels/SBO
The Systems Biology Ontology (SBO) is a set of controlled, relational vocabularies of terms commonly used in Systems Biology, and in particular in computational modeling.
biosimulators computational-biology mathematical-modeling numerical-simulation obofoundry ontology sbml systems-biology
Last synced: 11 Mar 2025
https://github.com/obophenotype/c-elegans-gross-anatomy-ontology
C. elegans Gross Anatomy Ontology
anatomy caenorhabditis-elegans obofoundry ontology
Last synced: 16 Apr 2026
https://github.com/IHCC-cohorts/GECKO
Genomics Cohorts Knowledge Ontology
cohort genomics obofoundry ontology
Last synced: 11 Mar 2025
https://github.com/incatools/environments2wikidata
Mapping of GAZ and ENVO to Wikidata
environmentontology envo gaz mapping obofoundry sssom wikidata
Last synced: 04 Mar 2026
https://github.com/glygen-glycan-data/gnome
GNOme - Glycan Naming and Subsumption Ontology.
glycans obofoundry subsumption
Last synced: 11 Feb 2026
https://github.com/biopragmatics/obo-db-ingest
🗄️ Conversion of biomedical nomenclatures like HGNC to OBO
biocuration obo obofoundry obographs obographviz ontologies owl rdf
Last synced: 14 Jul 2025
https://github.com/obophenotype/porifera-ontology
An ontology covering the anatomy of Porifera (sponges)
anatomy anatomy-ontology evodevo metazoa obofoundry ontology porifera sponges
Last synced: 16 Apr 2026
https://github.com/obophenotype/dicty-phenotype-ontology
Dicty Phenotype Ontology
obofoundry ontology phenotypes
Last synced: 16 Apr 2026
https://github.com/NuriaQueralt/covid19-epidemiology-ontology
Epidemiology and monitoring ontology for COVID-19
axiom-patterns biohackeu20 covid-19 epidemiology obo obofoundry ontology owl
Last synced: 11 Mar 2025